Home > About us > News > Content
​Small Methods (IF 12.13) - Surgical Navigation for Malignancies Guided by Near-Infrared-II Fluorescence Imaging, by Prof GJ Zhang's team
Pubdate: 2021/01/28 Hits:

Published online on January 18, 2020, Prof Zhang’s team summarized the application of near-infrared-II fluorescence materials on cancer surgical navigation. The research was financially supported by 5 programs including the National Natural Foundation of China, etc. Co-first authors RQ Yang (doctoral student of the Medical School of Xiamen University), KL Lou (master student of the Medical School of Xiamen University) and PY Wang (Assistant Professor of the CAS Fujian Institute of Material Structure).

 

 

Near-infrared (NIR) fluorescence imaging is an emerging noninvasive imaging modality, with unique advantages in guiding tumor resection surgery, thanks to its high sensitivity and instantaneity. In the past decade, studies on the conventional NIR window (NIR-I, 750–900 nm) have gradually focused on the second NIR window (NIR-II, 1000–1700 nm). With its reduced light scattering, photon absorption, and auto-fluorescence qualities, NIR-II fluorescence imaging significantly improves penetration depths and signal-to-noise ratios in bio-imaging. Recently, several studies have applied NIR-II imaging to navigating cancer surgery, including localizing cancers, assessing surgical margins, tracing lymph nodes, and mapping important anatomical structures. These studies have exemplified the significant prospects of this new approach. In this review, several NIR-II fluorescence agents and some of the complex applications for guiding cancer surgeries are summarized. Future prospects and the challenges of clinical translation are also discussed.

 

Full text: https://doi.org/10.1002/smtd.202001066.

Copyrights © 2020 Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer / The Key Laboratory for Endocrine-Related Cancer Precision Medicine of Xiamen. All rights reserved. Republication or redistribution of material on this website is prohibited without the prior written consent of Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer / The Key Laboratory for Endocrine-Related Cancer Precision Medicine of Xiamen.

The information and contents on this website are provided for general information purposes and references only, and on the understanding that no any medical/academic advice or recommendation is being rendered or given. All information and contents are not warranted to be absolutely correct, accurate, complete or up-to-date. All materials and functions are not warranted to be uninterrupted, error-free or virus/harmful element-free. We are entitled to delete, suspend or edit any information (including but not limited to service details and charges), contents and materials and stop any functions from time to time without prior notice or giving any reasons. We accept NO responsibility for any losses, damages or misunderstandings incurred for any causes whatsoever in relation to or as a result of the use of this website.