Mrs Jing-Wen Bai, MD supervised by Mr Guo-Jun Zhang who is the Professor of Changjiang Scholarship Program. From 2015 to 2016, she studied at Cedars-Sinai Medical Center, University of California, Los Angeles, USA. She mainly engaged in molecular biological mechanism (transcription factor Slug, Notch signaling pathway epigenetic regulation, epithelial-mesenchymal transition, cell cycle research) and the use of molecular imaging methods to evaluate the efficacy of anti-cancer drugs. She presided over/participated in 6 national, provincial and municipal fund projects, published 14 papers on SCI-listed journals such as PNAS, Leukemia, Theranostics, Oncogenesis, etc, and won 1 silver prize of Science and Technology Award of China Anti-Cancer Association.

Selected publications

1. Bai JW, Wei M, Li JW, Zhang GJ. Notch Signaling Pathway and Endocrine Resistance in Breast Cancer. Frontiers in Pharmacology 2020, 11: 924.

2. Bai JW, Chen, Mn, Wei XL, Li YC, Lin HY, Chen M, Li JW, Du CW, Kwan Man, Zhang GJ. The zinc-finger transcriptional factor Slug transcriptionally downregulates ERalpha by recruiting lysine-specific demethylase 1 in human breast cancer, Oncogenesis, 2017;6(5): e330.

3. Bai JW, Zhang YQ, Li YC, Zhang GJ. Analysis of epithelial-mesenchymal transition induced by overexpression of Twist, Methods in Molecular Biology, 2017;1652:259-74.

4. Bai JW, Li YC, Zhang GJ. Cell cycle regulation and anticancer drug discovery, Cancer Biology & Medicine, 2017;14(4):348-62.

5. Cao Q, Zhao X, Bai JW, Gery S, Sun HB, Lin DC, Chen Q, Chen ZS, Mack L, Yang H, Deng RS, Shi XP, Chong LW, Cho H, Xie JJ, Li QZ, Müschen M, Atkins AR, Liddlel C, Yu RT, Alkan S, Said JW, Zheng Y, Downes M, Evans RM, Koeffler HP. Circadian clock cryptochrome proteins regulate autoimmunity, Proc Natl Acad Sci USA, 2017;114(47):12548-53.