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Mrs Hui-Min SunAssistant researcher

Mrs Hui-Min Sun, assistant researcher, graduated from the School of Life Sciences of Shanxi Normal University in 2009 with a PhD, completed postdoctoral research of molecular system evolution in the Preventive Medicine Department in 2016, and then worked for the role and mechanism of protein kinase TOPK in the progression of urinary system tumors in Xijing Hospital of the Fourth Military Medical University. At present, she devotes to the mechanism of TKI-resistant metastasis of renal cell carcinoma and the regulation of vascular permeability by exosomes. She presided over each of NSFC youth fund, feneral fund and postdoctoral fund, general project of Fujian Natural Science Foundation, the emergency scientific research project of new coronavirus prevention and control of Xiamen University, and the Xiamen Science and Technology Project. Moreover, she participated in a NSFC general project international cooperation project. 9 SCI-listed papers published.

Selected publications

1. Yue JT, Sun HM, Liu SJ, Yu F, Wang SS, Wang Fl, Shen RX, Zhu F, Zhang L, Shao C. Down regulation of NDR1 contribute to metastasis of prostate cancer cells via activating epithelial-mesenchymal transition. Cancer Medicine. 2018; 7:3200–12.

2. Xue PP, Zeng FF, Duan QH, Xiao JJ, Liu L, Yuan P, Fan LN, Sun HM, Malyarenko OS, Lu H, Xiu RJ, Liu SQ, Shao C, Zhang JM, Yan W, Wang Z, Zheng JY, Zhu F. BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer. EBioMedicine, 2017, 20:50-60.

3. Vishchuk O, Sun HM, Wang Z, Ermakova S, Xiao JJ, Lu T, Xue PP, Zvyagintseva T, Xiong H, Shao C, Yan W, Duan QH, Zhu F. PDZ-Binding Kinase/T-LAK Cell-Originated Protein Kinase is a target of the fucoidan from brown alga Fucus evanescens in the prevention of EGF-induced neoplastic cell transformation and colon cancer growth. Oncotarget. 2016,7(14):18763-73.

4. Sun HM, Zhang L, Shi CH, Hu PZ, Yan W, Wang Z, Duan QH, Lu F, Qin LP, Lu T, Xiao JJ, Wang YM, Zhu F, Shao C. TOPK is highly expressed in circulating tumor cells, enabling metastasis of prostate cancer. Oncotarget, 2015, 6(14):12392-404.

5. Sun HM, Tang XF, Wang B, Zhang JX, Cheng H, Su HX, Li F, Men K, Zhao L, Xu JQ, Yu XH, Tan YH, Yan YP, Xu DJ. The preliminary study on molecular evolution of two routes of intrauterine transmission of Hepatitis B virus. Arch Virol, 2012, 157:155–64.


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