Prof Min Chen is a master supervisor and deputy director of the Central Clinical Research Core of Xiang’an Hospital. She graduated from Heidelberg University in Germany in 2000, and then completed postdoctoral research in University of Texas. After that, she worked as assistant professor or above in many research institutions in the United States. Upon returning to China in 2014, she worked as a researcher in Shantou University Medical College. In 2018, she moved to Xiang’an Hospital of Xiamen University and held the current positions. She mainly engaged in the research of function and mechanism of circRNA in breast cancer, as well as the preclinical and clinical research of multi-mode molecular imaging probes with near infrared fluorescence as the core. She hosted or participated in 3 national and provincial scientific research projects, published 14 SCI-listed papers, and won the silver prize of Science and Technology Award of the China Anti-cancer Association.

Selected publications

1. Xu JZ, Shao CC, Wang XJ, Zhao X, Chen JQ, Ouyang YX, Feng J, Zhang F, Huang WH, YQ, Chen CF, Wei XL, Dong HY, Zhang GJ, Chen M. circTADA2As suppress breast cancer progression and metastasis via targeting miR-203a-3p/SOCS3 axis. Cell Death and Disease, 2019, 10(3): 175-91.

2. Li RH, Min C, Liu J, Shao CC, Guo CP, Wei XL, Li YC, Huang WH, Zhang GJ. Long noncoding RNA ATB promotes the epithelial−mesenchymal transition by upregulating the miR-200c/Twist1 axe and predicts poor prognosis in breast cancer, Cell Death and Disease，2018, 9 (12): 1171-87.

3. Wen XF, Min C, Wu Y, Chen MN, Glogowska Aleksandra, Klonisch Thomas, Zhang GJ.  Inhibitor of DNA binding 2 inhibits epithelial-mesenchymal transition via upregulation of Notch3 in breast cancer, Translational Oncology, 2018, 11(5): 1259-70.

4. Lin HY, Liang YK, Dou XW, Chen CF, Wei XL, Zeng D, Bai JW, Guo YX, Lin FF, Huang WH, Du CW, Li YC, Min C, Zhang GJ. Notch3 inhibits epithelial-mesenchymal transition in breast cancer via a novel mechanism, upregulation of GATA-3 expression, Oncogenesis, 2018, 7(8): 59-73.

5. Dou XW, Liang YK, Lin HY, Wei XL, Zhang YQ, Bai JW, Chen CF, Min C, Du CW, Li YC, Tian J, Man Kwan; Zhang GJ. Notch3 Maintains Luminal Phenotype and Suppresses Tumorigenesis and Metastasis of Breast Cancer via Trans-Activating Estrogen Receptor-α, Theranostics, 2017, 7(16):4041-56.